Chimera brains are found in the northwest part of the Calm Lands and they’re not too rare.

You can steal Lv. 4 Key Spheres from the Monster Arena creation Nemesis by defeating it. This will give you access to the Lv. 4 Key Sphere ability.

This setup requires a lot of work. ..

After capturing ten of every monster in Spira, as well as defeating all the other Original Creations in the Monster Arena, Nemesis is a substantial amount of work to go the stealing route for more Lv. 4 spheres.

The main story progresses and you’ll find Lv. 4 Key Spheres in chests on Mt. Gagazet, Inside Sin, and in the Omega Ruins.

What Are These Used For?

The Lv. 4 Key Sphere is a key item used to unlock level four locks on the Sphere Grid.

To unlock every Lv. 4 lock on the grid, you’ll need x12 of these spheres.

In Final Fantasy X, unlocking those locks is really the Lv. 4 Key Sphere’s only purpose. But it’s important! All of the most powerful spells, such as Ultima and Flare, are locked with fourth-level locks. ..

You can be sure that spending a Lv. 4 Key Sphere will always reward you with something great.

Rikku can use her spheres to create powerful mixes.

The trio of nine999 (Winning Formula, Lv. 4 Key Sphere, and all current allies) deal 9999 damage with every attack until the end of battle.

This item casts Shell, Protect, Haste, and Regen on the party.

The Super Elixir can cure all negative status effects and restore the party’s HP and MP to full.

Are These Worth Farming?

I can provide more Sphere Grid if you need it.

The Lv. 4 Key Sphere is a powerful item that opens up some of the best abilities and spells in the game.

Earn these spheres to increase your power. It may take time and some Gil, but trust me when I say it will all be worth it in the end. ..