Bloodborne’s end-game areas are filled with horrors that can cause Frenzy, and sedatives are one of the few ways to avoid it. To get them, you’ll need to find and purchase them from merchants in the game’s various areas.
Lecture Building Farming (late-game)
After defeating The One Reborn, you’ll find yourself in the Lecture Building, a small area that houses the best Sedative farm in the game. ..
Head out the door in front of you and turn left before running down this walkway all the way to the end of the building. From the 2nd Floor Lecture Building Lamp, head out the door in front of you and turn left before running down this walkway all the way to the end of the building. ..
After passing by the Slime students, turn right at the end of the path to find a giant skeleton in the corner, guarding a hatch in the floor. ..
Sprint past the large skeleton and roll into the hatch behind it. You’ll find yourself in a room with a giant spider named Patches. ..
Talk to or kill Patches to get it to move from the door, then head through it and out into the Lecture Building on the first floor. Open the door opposite to you to find the Lecture Building Lamp. ..
The farm begins here, with the first row of crops. ..
You’ll need to create a new user account on the site. ..
Walk outside the Lecture Building and turn right into the massive corridor.
Inside the room, you’ll find a set of cabinets that are being illuminated by a lantern. Approach them and enter the room next to it. Inside, you’ll find a treasure chest. ..
This room and the door on the other side lead to a deserted lecture hall.
Head towards the dead lecturer and loot the Lecture Theatre Key off of his body. This key will open the room that holds the targets of the farm. ..
As you approach the end of the large corridor, turn left and continue walking up the corridor.
When you see an unassuming door hidden between two pillars, keep your camera pointed towards the right wall until you see an opportunity to take a picture.
The Lecture Theatre Key opens the door to the Lecture Theatre, and allows you access to fight off a small army of Slime Students.
It’s these enemies that drop the Sedatives that you’re after, so retreat slightly and bide your time for a safe opening to run in and take them out.
After slaying all of the zombies in the room, open the door on the right side to find a small research room. ..
If you open the other door in this room, you’ll find yourself back in the central corridor, right next to the Lecture Building Lamp. ..
This newly opened door will provide a shortcut for you to reach the Students on repeat runs of the farm.
With the lecture hall and shortcut open, you’re now ready to respawn the Slime Students by warping to the Hunter’s Dream and back again.
Slime students are a rare breed of enemy, and sedatives are one of the most common drops from them. Farming these enemies is the quickest way to stock up on sedatives. ..
The best way to get students to take their medication is to use a shortcut. Each time you repeat the farm, only take a couple of minutes and you’ll likely get at least one student to drop some sedatives.
Buying Sedatives in the Hunter’s Dream (New Game + only)
The Hunter’s Dream Messenger Shop is a convenient way to stock up on Sedatives quickly, as it offers a wide variety of products that are perfect for use in the game.
Unfortunately, it’s not as simple as just buying them.
To access the Upper Cathedral Ward, you’ll first have to acquire the Cosmic Eye Watcher Badge from Upper Cathedral Ward. And to access the Upper Cathedral Ward, you’ll have to grab the Upper Cathedral Ward Key from a hidden corner of Yahar’gul.
The Yahar’gul, Unseen Village Lamp is a place where you can start your day.
From the lamp, head down the small set of stairs to the left. Then sprint down the massive staircase full of villagers. ..
When you reach the bottom of the staircase, turn right and head out the door. ..
The door to the left of the closed door leads down a spiral staircase.
The Brick Troll is a large, green creature that lives in the corridors of the castle. It is difficult to defeat it, but it is worth your time. You can run to the end of the corridor and defeat it before walking through the metal gate to your right.
When you reach the bottom of the stairs, turn left and walk through the door to find yourself back outside. Walk down the stairs to find yourself on a small walkway that circles around a fountain. ..
As you walk up the set of stairs, turn left and sprint towards safety. ..
You see a hole in the metal railing to your right, and you need to find a way to get past it.
Step off the ledge carefully to safely land on a hidden ledge below.
You see a large door to your right. Go through it and defeat the Brick Troll to your right. ..
The Upper Cathedral Ward Key is a key that unlocks the cages in the Upper Cathedral Ward.
With the key picked up, warp back to the Lamp before warping again to the Hunter’s Dream.
To reach the Upper Cathedral Ward, head to the gravestone in Cathedral Ward and use it to warp to the lamp in the Upper Cathedral Ward. ..
Walk down the stairs ahead and turn right into the small corridor that leads to an elevator. Take the elevator ride up to find yourself in the Healing Church Workshop.
Step out onto the Healing Church Workshop tower and take the left path.
Walk inside, clear out the enemies, and ascend the stairs to the top of the tower.
The two Riflemen are guarding a corridor behind them.
After defeating the enemies, head down this corridor and use the Upper Cathedral Ward Key to unlock the door at its end. ..
The Upper Cathedral Ward is a popular tourist destination for visitors to Edinburgh. The bridge that leads to the Choir Building is a popular spot for photos and overlooks the city below. ..
Defeat the enemies on this bridge, then light the Upper Cathedral Ward Lamp to give yourself a close location to respawn at in case you fall victim to the residents of the Choir Building. ..
This building is often considered the most dangerous area in the entire game. So be sure to understand the route to the Cosmic Eye Watcher Badge fully before heading in.
The giant gold doors lead to a secret room.
Avoid the Frenzy-inflicting Slugs and head up the narrow staircase towards the Church Servant at the top.
Church servant blocks your way into building, so you’ll probably have to kill it. ..
Despite this Servant’s increased strength, it is still very susceptible to gun parries. So parry and riposte a couple times and you’ll gain safe entry into the building.
Inside the building, head to the left and take out the Brainsucker enemy. ..
The Brainsuckers are a powerful enemy that can stunlock players with their powerful attacks. It is important to rush towards them and stay aggressive in order to kill them quickly.
The Werewolf is a potential danger in this room, so be careful as you head deeper into the building.
The Brainsucker is a difficult enemy to kill. You need to get its attention and then sprint back to the room in which you killed it. The Werewolf will get stuck in the doorframe, allowing for an easy kill. ..
After dispatching the Werewolf, head back out into the corridor and turn left before running to the end of the hallway. Ahead of you is a door – go through it and prepare to run away from three more Werewolves. ..
You just came through the door and werewolves are following you. You need to trap them and repeat the trick you did earlier.
Once you’ve killed all three Werewolves, head down the stairs to your right and walk back out into the new area.
The final Werewolf is the last enemy you’ll face in the game. It’s located at the bottom of the stairs, and drawing its attention will cause it to attack. ..
You can lure this Werewolf back to the last door to stay safe, or use the wide open space to take down the Werewolf the honorable way.
Walk towards the archway until you find a large door.
Through this doorway is a thin corridor with a Brainsucker and an item next to a corpse. Defeat or run past the Brainsucker, and pick up the Cosmic Eye Watcher Badge from this corpse.
You can finally purchase an infinite supply of Sedatives to help you through the Nightmare Realm.
